A beginner's CSS (Cascading Style Sheets) course usually begins with an introduction to the basics of CSS, including selectors, properties, and values. It covers how CSS is used to style HTML elements, such as changing colors, fonts, sizes, margins, paddings, and positioning. The course may delve into the box model, floats, flexbox, and grid layout systems for creating responsive designs. Additionally, it may explore CSS preprocessors like Sass and the use of frameworks like Bootstrap for faster development. Throughout the course, hands-on exercises and projects are often provided to reinforce concepts and practical skills.